• Motion

    Graphics

  • Medical

    Animation

  • Medical

    Illustration

  • Biomedical

    Vizualization

  • Art

    Direction

  • Graphic

    Design

PROJECT SNAPSHOTS

Showreel

Case Study

Duchenne muscular dystrophy (DMD) is the most common neuromuscular disease and affects all world populations equally.

The cause of this genetic disease is loss of a single protein, dystrophin, in all types of muscle (ie, skeletal, cardiac, and smooth) and in neurons. The loss of protein function is the consequence of mutations in the large DMD gene.

  • Client

    Serepta Therapeutics

  • Deliverables

    Illustrations

  • Use

    Stakeholder Presentation

Dystrophin Replacement

Innovative therapeutic approaches for DMD have emerged in the past 30 years, with many in clinical trials. These include slowing the progression of the disease by immune modulators (eg, steroids and transforming growth factor-β inhibitors), inducing or introducing proteins that may compensate for dystrophin deficiency in the myofiber (eg, utrophin, biglycan, and laminin), or bolstering the muscle’s regenerative response (eg, myostatin and activin 2B). A parallel approach places dystrophin back into patient muscle.



Figures

Muscle Fiber
Cell Membrane

Creativity redefined. Offering a unique approach to every aspect of design and the result is simply stunning.